• Achieving hidradenitis suppurativa response score is associated with significant improvement in clinical and patient-reported outcomes: Post hoc analysis of pooled data from PIONEER I and II 

      Kimball, Alexandra Boer; Tzellos, Thrasyvoulos; Calimlim, Brian M; Teixeira, Henrique D; Geng, Ziqian; Okun, Martin M (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-07)
      Hidradenitis Suppurativa Clinical Response (HiSCR), is a validated tool that has been used to assess the efficacy of adalimumab among patients with hidradenitis suppurativa. We evaluated the clinical meaning of HiSCR by relating it to patient-reported outcomes to give further context to its achievement in a post hoc analysis of integrated data from two phase 3 clinical trials (PIONEER I and II). ...
    • Baseline Demographics, Comorbidities, Treatment Patterns and Burden of Atopic Dermatitis in Adults and Adolescents from the GLOBOSTAD Long-Term Observational Study 

      Calzavara-Pinton, Piergiacomo; Čelakovská, Jarmila; Lapeere, Hilde; Holzer, Gregor; Al-Ahmad, Mona; Chu, Chia-Yu; Ferrucci, Silvia M.; Kataoka, Yoko; Rossi, Mariateresa; Fomina, Daria S.; Chung, Wen-Hung; Tzellos, Thrasyvoulos; Fougerousse, Anne-Claire; Wu, Jiangming; Ardeleanu, Marius; Ozturk, Zafer E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-06)
      Introduction - Insights into real-world treatment of atopic dermatitis (AD) are relevant to clinical decision making. The aim of this analysis was to characterize patients who receive dupilumab for AD in a real-world setting.<p> <p>Methods - The GLOBOSTAD registry is an ongoing, longitudinal, prospective, observational study of patients with AD who receive dupilumab according to country-specific ...
    • Factors associated with treatment satisfaction in patients with hidradenitis suppurativa: results from the Global VOICE project 

      Midgette, Bria; Strunk, Andrew; Akilov, Oleg; Alavi, Afsaneh; Ardon, Christine; Bechara, Falk G.; Cohen, Arnon D.; Cohen, Steven; Daveluy, Steven; del Marmol, Véronique; Delage, Maïa; Esmann, Solveig; Fisher, Shani; Giamarellos-Bourboulis, Evangelos J.; Glowaczewska, Amelia; Goldfarb, Noah; Brant, Elena Gonzalez; Grimstad, Øystein; Guilbault, Sandra; Hamzavi, Iltefat; Hughes, Rosalind; Ingram, John R.; Jemec, Gregor B.E.; Ju, Qiang; Kappe, Naomi; Kirby, Brian; Kirby, Joslyn S.; Lowes, Michelle A.; Matusiak, Lukasz; Micha, Stella; Micheletti, Robert; Miller, Angela P.; Moseng, Dagfinn; Naik, Haley; Nassif, Aude; Nikolakis, Georgios; Paek, So Yeon; Pascual, Jose Carlos; Prens, Errol; Resnik, Barry; Riad, Hassan; Sayed, Christopher; Smith, Saxon D.; Soliman, Yssra; Szepietowski, Jacek C.; Tan, Jerry; Thorlacius, Linnea; Tzellos, Thrasyvoulos; van der Zee, Hessel H.; Villumsen, Bente; Wang, Lanqi; Zouboulis, Christos; Garg, Amit (Journal article; Tidsskriftartikkel, 2022-12-01)
      <p><i>Background</i> Nearly half of patients with hidradenitis suppurativa (HS) report dissatisfaction with their treatment. However, factors related to treatment satisfaction have not been explored. <p><i>Objectives</i> To measure associations between treatment satisfaction and clinical and treatment‐related characteristics among patients with HS. <p><i>Methods</i> Treatment satisfaction was ...
    • Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization - systematic review and recommendations from the HS ALLIANCE working group 

      Zouboulis, Christos C.; Bechara, Falk Georges; Dickinson-Blok, Janine L.; Gulliver, Wayne Peter Frances; Horváth, Barbara H.; Hughes, Rosalind; Kimball, Alexandra Boer; Kirby, Brian; Martorell, Antonio; Podda, Maurizio; Prens, Errol Prospero; Ring, Hans Christian; Tzellos, Thrasyvoulos; van der Zee, Hessel H.; van Straalen, Kelsey R.; Vossen, Allard R.J.V.; Jemec, Gregor Borut Ernst (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-03)
      Hidradenitis suppurativa (HS)/acne inversa is a debilitating chronic disease that remains poorly understood and difficult to manage. Clinical practice is variable, and there is a need for international, evidence‐based and easily applicable consensus on HS management. We report here the findings of a systematic literature review, which were subsequently used as a basis for the development of international ...
    • Impact of hidradenitis suppurativa on work loss, indirect costs and income 

      Tzellos, Thrasyvoulos; Yang, H; Mu, F; Calimlim, B; Signorovitch, J (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-18)
      Background Hidradenitis suppurativa (HS), a chronic cutaneous disease, can negatively affect work life. Objectives This retrospective cohort study evaluates the indirect burden among employed patients with HS in the U.S.A.<p> <p>Methods Newly diagnosed and general patients with HS, who were employees (age 18–64 years) from a large claims database (Q1 1999 to Q1 2015), were matched 1 : 5 to ...
    • Review of Comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice 

      Tzellos, Thrasyvoulos; Zouboulis, Christos C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-18)
      Hidradenitis suppurativa (HS) is a chronic, recurrent skin inflammatory disease associated with a variety of comorbidities, like reduced quality of life, metabolic syndrome, sexual dysfunction, working disability, axial spondyloarthritis, inflammatory bowel disease, depression, and anxiety. Like psoriasis, HS patients have been found to have higher risk of cardiovascular death and suicide risk. ...